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Iron Profile (Transferrin & Transferrin Saturation)
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Iron Profile
Longitudinal Data
| Date | Transferrin Saturation | Transferrin | Context/Notes | Source |
|---|---|---|---|---|
| 2025-11-17 | 16.5% (N) | 1.86 g/L (L) | KIMS — anemia workup. Ref: 15–45% (TSAT), 2–3.60 g/L (Transferrin) | Ishamma T M 13.pdf |
Interpretation
Iron studies drawn 2025-11-17 as part of the pancytopenia/anemia workup ordered by Dr. Mithun Padmanabhan:
- Transferrin saturation: 16.5% — within normal range (15–45%), suggesting iron stores are not depleted.
- Transferrin: 1.86 g/L — low (reference 2–3.60 g/L). Low transferrin in the setting of normal TSAT is consistent with anemia of chronic disease / inflammation rather than iron deficiency. Transferrin is a negative acute-phase reactant — it decreases during inflammatory states, which is consistent with the concurrent ESR of 130 mm/hr and CRP of 13.8 mg/L at that time.
[!note] Clinical Significance
The iron profile pattern (normal TSAT + low transferrin) helps classify the anemia as non-iron-deficient. This supported the clinical suspicion that the pancytopenia was due to a primary bone marrow process rather than nutritional deficiency. Combined with normal folic acid (>20 ng/ml, see Folic Acid), iron deficiency and folate deficiency were both ruled out.
Related Pages
- Folic Acid — Normal folate from same date
- Anemia — The clinical picture
- Aml — Ultimately diagnosed as the cause
- Peripheral Smear 2025 11 17 — PBF from same date
Source: raw/labs/Ishamma T M 13.pdf