labs

White Blood Cell Count (WBC)

White Blood Cell Count (WBC)

Longitudinal Data

Date Value Flag Context/Notes Source
2026-06-06 2500 L KIMS — Flow cytometry. Bill L042743426. RECOVERY +300 from June 1. Polymorphs 49.3%, Lymphs 35.5%, Monos 9.2%, Eos 3.6%, Baso 2.4% (H). ANC 1240 (L — moderate neutropenia, improved from severe). ALC 890 (L), AMC 230 (N), AEC 90 (N), ABC 60 (N). Hb 12.1 (N — RECOVERED TO NORMAL), Plt 241 (N — stable). Dr. Bijay. Collected 10:50 AM. raw/labs/2026-06-07_Ishamma_T_M_1.pdf
2026-06-01 2200 L KIMS — Flow cytometry. Bill L041256126. DEEPEST NADIR — further decline −200 from May 27. Polymorphs 46%, Lymphs 42.8% (relative lymphocytosis), Monos 5.6%, Eos 3.7%, Baso 1.9% (H). ANC 990 (L — SEVERE NEUTROPENIA). ALC 920 (L), AMC 120 (L), AEC 80 (L), ABC 40 (L). Hb 11.3 (L — dropped), Plt 252 (N — fully recovered). Dr. Bijay. Collected 11:11 AM. raw/labs/2026-06-01_Ishamma_T_M.pdf
2026-05-27 2400 L KIMS — Flow cytometry. Bill L040020926. Continued decline — leukopenia deepening. Polymorphs 61.3%, Lymphs 31.1%, Monos 5.5%, Eos 1.3%, Baso 0.8%. ANC 1460 (L — moderate neutropenia). ALC 740 (L), AMC 130 (L). Hb 12.0 (N — first normal), Plt 107 (L). Dr. Bijay. raw/labs/20260527_Ishamma T M 1 5-27-2.pdf
2026-05-23 3500 L KIMS — Flow cytometry. Bill L038904126. Polymorphs 68.8%, Lymphs 24.1%, Monos 4.5%, Eos 2.3%, Baso 0.3%. ANC 2430 (N borderline), ALC 850 (L), AMC 160 (L). Smear checked. Dr. Bijay. raw/labs/20260527_Ishamma T M 5-27-1.pdf
2026-05-17 4600 N KIMS — Flow cytometry. Bill L037179526. Decreased −1100 from May 11, still within normal. ANC 3400 (N). Plt 103 (L). Polymorphs 74.7%, Lymphs 16.3% (L). Dr. Bijay. raw/labs/2026-05-17_Ishamma_T_M_1.pdf
2026-05-11 5700 N KIMS — Flow cytometry. Bill L035372426. Continued normal, +1700 from May 4. ANC 3950 (N). Plt 113 (L — dropped). Dr. Bijay. raw/labs/2026-05-11_Ishamma_T_M_A.pdf
2026-05-04 4000 N KIMS — Flow cytometry. Bill L033433126. Recovered to normal from 3000 (Apr 27). ANC 2360 (N). Plt 213 (stable). raw/assets/2026-05-04_Ishamma_T_M.pdf
2026-04-27 3000 L KIMS — Flow cytometry. Bill L031606726. Leukopenia; ANC 1990 (L — mild neutropenia). Plt recovered to 196 (N). raw/labs/20260427_Ishamma T M 1 ok.pdf
2026-04-20 4100 N KIMS — Flow cytometry. Bill L029731026. 20260420_Ishamma T M today.pdf
2026-04-13 3500 L KIMS Ishamma T M 1.pdf
2026-04-06 5400 N KIMS Ishamma T M.pdf
2026-03-30 4300 N KIMS Ishamma T M 2.pdf
2026-03-25 5400 N KIMS Ishamma T M 1 2.pdf
2026-03-18 6000 N KIMS Ishamma T M 1 3.pdf
2026-03-12 7100 N KIMS Ishamma T M 1 4.pdf
2026-03-05 3500 L KIMS Ishamma T M 3.pdf
2026-03-02 3000 L KIMS Ishamma T M 4.pdf
2026-02-25 2400 L KIMS Ishamma T M 5.pdf
2026-02-23 2300 L DDRC Report For Accession No 4170ZB001398.pdf
2026-02-20 1600 L DDRC - Critical 4170ZB0011814170_849900t.pdf
2026-02-17 1600 L KIMS Ishamma 1.pdf
2026-02-10 1300 L KIMS - Nadir during treatment Ishamma T M 6.pdf
2026-02-04 4100 N KIMS Ishamma T M 1 5.pdf
2026-01-31 4200 N KIMS Ishamma T M 7.pdf
2026-01-28 4000 N KIMS Ishamma T M 1 6.pdf
2026-01-25 5900 N KIMS Ishamma T M 8.pdf
2026-01-22 6800 N KIMS Ishamma T M 9.pdf
2026-01-19 5000 N KIMS Ishamma T M 1 7.pdf
2026-01-16 5400 N KIMS Ishamma T M 10.pdf
2025-11-28 2500 L KIMS File1000384802.pdf
2025-11-19 2320 L DDRC CCR_4182YK007572_296266q.pdf
2022-11-25 10500 N JDC Lab (Jothydev's) — Impedance. Ref 4000–11000. Dr. Arun Shankar. Normal. Neutrophils 80% (H), Lymphs 17%, Eos 3%. 2 months after Sep 2022 acute inflammation. raw/assets/20260429_IMG_9751.jpeg
2022-09-27 9550 N DDRC SRL 4182VI0131054182_816476x.pdf
2022-09-20 14770 H DDRC SRL - During acute inflammation 4182VI0091894182_910394a.pdf

Trend Analysis

WBC was normal-to-elevated in September 2022 (14770 during acute inflammation, normalizing to 9550). At AML diagnosis in November 2025, WBC was leukopenic at 2320-2500. With initiation of Aza-Ven treatment, WBC normalized through January 2026 (range 4000-6800). However, a significant treatment-related myelosuppressive nadir occurred in February 2026, with WBC dropping to a critical low of 1300 on 2026-02-10 and remaining critically low at 1600 through mid-to-late February. Recovery began in early March, with WBC returning to the normal range (4300-7100) by mid-to-late March 2026.

April 2026 pattern: WBC dipped to 3500 (Apr 13), then briefly recovered to 4100 (Apr 20), then dropped again to 3000 cells/cumm (Apr 27) — back into leukopenic range. This oscillation is consistent with cyclical Aza-Ven myelosuppression.

May 2026 pattern: WBC recovered to 4000 cells/cumm (May 4) — exactly at the lower limit of normal, representing resolution of leukopenia from Apr 27. By May 11, WBC increased further to 5700 cells/cumm — solidly within normal range (+1700 from May 4). ANC also remained normal at 3950. However, platelets simultaneously dropped sharply from 213K → 113K (May 4 → May 11), demonstrating dissociated lineage kinetics where platelet suppression (early Aza-Ven nadir) precedes white cell suppression by several days.

May-June 2026 nadir pattern (confirmed and extended): The WBC/ANC nadir deepened beyond initial expectations:
- May 17: WBC 4600 (N, declining) / ANC 3400 (N, declining)
- May 23: WBC 3500 (L — leukopenia) / ANC 2430 (N borderline)
- May 27: WBC 2400 (L — deepening leukopenia) / ANC 1460 (L — moderate neutropenia)
- June 1: WBC 2200 (L — DEEPEST NADIR) / ANC 990 (L — SEVERE NEUTROPENIA)

[!success] WBC/ANC NADIR RESOLVED: RECOVERY INITIATED (June 6)
WBC has increased to 2500 cells/cumm (+300 from June 1) and ANC to 1240 cells/cumm (+250 from June 1). The June 1 nadir — the deepest WBC/ANC nadir since treatment stabilization (WBC 2200, ANC 990 — severe neutropenia Grade 3) — has resolved.

June 6 recovery indicators:
- ANC 1240 (moderate neutropenia) — upgraded from severe (990) to moderate, now above the critical <1000 threshold
- Polymorphs 49.3% — increased from 46% (June 1), relative lymphocytosis resolving
- Lymphs 35.5% — decreased from 42.8% (June 1), normalizing differential
- Concurrent Hb 12.1 g/dL (N)RECOVERED TO NORMAL from 11.3 (June 1), first normal since May 27
- Platelets 241K (N) — stable normal, fully recovered

Recovery trajectory from June 1 nadir:
- WBC: 2200 → 2500 (+14%)
- ANC: 990 → 1240 (+25% — EXITED SEVERE NEUTROPENIA)
- Hb: 11.3 → 12.1 (+0.8 g/dL — NORMALIZED)
- Plt: 252K → 241K (stable normal)

Expected continued recovery: Based on prior cycle patterns, WBC/ANC should continue rising over the next 3-7 days, crossing into normal range (WBC >4000, ANC >2000) by ~June 9-13. Infection risk downgraded from critically elevated to elevated. Continue acyclovir and posaconazole prophylaxis. See Anc, Hemoglobin, Platelet Count.

Nov 2022 context: WBC 10,500 was normal (ref 4000–11000). Neutrophil differential 80% was elevated (ref 45–75%), suggesting residual subclinical inflammation or stress neutrophilia.